Synthesis of Physiologically Potent β-Amino Alcohols
- 15 July 2004
- journal article
- account
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 2004 (10) , 1673-1685
- https://doi.org/10.1055/s-2004-829578
Abstract
We have established practical protocols to the stereoselective synthesis of syn- and anti-β-amino alcohols via the electrophile-promoted intramolecular amination of trichloroacetimidates derived from allylic and homoallylic alcohols. Stereoselective total synthesis of natural products containing β-amino alcohol functionality has been achieved by means of these methods.Keywords
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