Asymmetric synthesis of taxol arid taxotère side chains by enolate hydroxylation
- 1 April 1996
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 74 (4) , 621-624
- https://doi.org/10.1139/v96-066
Abstract
We report an asymmetric synthesis of the taxol and taxotère side chains by hydroxylation of enolates derived from N-substitued methyl 3-amino-3-phenyl propionate with the oxodiperoxymolybdenum (pyridine) (hexamethyl phosphoric triamide) complex (MoOPH). Key words: taxol and taxotère side chains, hydroxylation.Keywords
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