Uniform light distribution in hollow organs by means of backscattering layers

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Abstract
The uniform distribution of light over the area to be photodynamically treated is one of the prerequisites for a successful tumor therapy. For homogenization of laser light distributions especially in hollow organs a new method has been developed. It applies fiber coupled emitters in combination with a highly backscattering layer deposited on the inner wall of the organ to be irradiated. The effect of homogenization by means of this layer has been calculated for spherical and cylindrical hollow organs and compared with experimental results. This method also seems to be applicable for organs with irregular geometry. Laser light applications for different medical fields will be described. Applying the same method, isotropic light detectors with diameters of less than 1 mm have been developed for irradiation control during photodynamic treatment or for determination of light distributions in tissue.

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