Synthesis of Analogues of Ribosylbarbituric Acid
- 1 September 1985
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 4 (4) , 465-476
- https://doi.org/10.1080/07328318508081293
Abstract
Syntheses of 5-alkyl (5 b,c), 2''-deoxyribosyl (9, 10) and arabinofuranosyl (13) analogues of ribosylbarbituric acid (5a) are described. The compounds were prepared by condensation of persilylated barbituric acid with pentofuranosyl moieties. The 2''-tolylthio analogue (16) was obtained by an alternative procedure involving ring-opening of 6,2''-O-cyclouridine (15).This publication has 14 references indexed in Scilit:
- Synthesis and physicochemical properties of 6-O-cyclopyrimidine nucleosides.CHEMICAL & PHARMACEUTICAL BULLETIN, 1982
- Reaction between 2,2′-anhydro-1-β-D-arabinofuranosyluracil and thiolate ionsJournal of the Chemical Society, Perkin Transactions 1, 1982
- Inhibition of orotidine-5'-phosphate decarboxylase by 1-(5'-phospho-.beta.-D-ribofuranosyl)barbituric acid, 6-azauridine 5'-phosphate, and uridine 5'-phosphateBiochemistry, 1980
- Orotidine 5'-monophosphate decarboxylase inhibitors formed by spontaneous reaction of barbituric acid and ribose 5-phosphate, a surprising reactionJournal of the American Chemical Society, 1980
- Nucleosides. LXV. Synthesis and reactions of some pyrimidine 2',6-anhydronucleosidesThe Journal of Organic Chemistry, 1970
- Carbon-13 magnetic resonance. XVIII. Selected nucleosidesThe Journal of Physical Chemistry, 1970
- Nucleosides. LVIII. Transformations of pyrimidine nucleosides in alkaline media. 3. Conversion of 5-halouridines into imidazoline and barbituric acid nucleosidesThe Journal of Organic Chemistry, 1969
- 06,5′-Cyclonucleosides. Reactions of 5-iodopyrimidine nucleosides with baseTetrahedron Letters, 1968
- Nucleosides. LII. Transformations of pyrimidine nucleosides in alkaline media. 1. Conversion of 5-haloarabinosyluracils to imidazoline nucleosidesThe Journal of Organic Chemistry, 1968