THE CONNECTIVE-TISSUE COMPONENT OF THE CAPRINE ARTHRITIS-ENCEPHALITIS SYNDROME

  • 1 January 1980
    • journal article
    • research article
    • Vol. 100  (2) , 443-454
Abstract
The gross and microscopic connective tissue lesions in 12 goats with caprine arthritis-encephalitis were described, including those from which a virus was isolated. Lesions were most often associated with synovial-lined structures, including joints, tendon sheaths and bursae, and were typified by synovial cell proliferation, subsynovial mononuclear cell infiltration, the presence of fibrin, fibrinous concretions necrosis and mineralization. Extrasynovial lesions were located in kidneys, vessels and brain. The inflammatory infiltrates in these organs were predominantly mononuclear. Amyloid was also found in liver, spleen and kidney. Microbiologic techniques failed to demonstrate any bacteria, Mycoplasma or Chlamydia in the lesions.