A versiconal hemiacetal acetate converting enzyme in aflatoxin biosynthesis
- 1 September 1989
- journal article
- research article
- Published by Springer Nature in Mycopathologia
- Vol. 107 (2-3) , 121-126
- https://doi.org/10.1007/bf00707548
Abstract
Conversion of the aflatoxin biosynthetic intermediate versiconal hemiacetal acetate (VHA) in a cell free extract ofAspergillus parasiticus ATCC 15517 is investigated. The enzymatic reaction is monitored by a method using high performance liquid chromatography (HPLC). The major product of the enzymatic reaction is a water soluble compound not chloroform-extractable at pH 7.5. The product becomes chloroform extractable upon acidification of the reaction medium and is separated and quantitated by reversed-phase HPLC. It is tentatively identified as ‘versiconal hemiacetal alcohol,’ which is converted to versicolorin C (VC) upon acid treatment.This publication has 19 references indexed in Scilit:
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