Intravenous Infusion of Amino Acids Stimulates Gastric Acid Secretion in Man

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Abstract
INTRAVENOUS alimentation with amino acids in combination with glucose, vitamins and minerals is commonly used in the treatment of patients who are unable to maintain adequate nutrition by feeding.1 Recent studies in man indicate that perfusion of the proximal small intestine with protein stimulates gastric acid secretion to approximately one third of maximal pentagastrin-stimulated acid output.2 Since the acid secretory effect of intestinal protein perfusion may in part be due to the absorption of amino acids and small peptides from the gut, we conducted experiments to determine whether intravenous infusion of amino acids stimulates gastric acid secretion in man.Methods . . .