The structural and functional heterogeneity of glutamic acid decarboxylase: A review
- 1 March 1991
- journal article
- review article
- Published by Springer Nature in Neurochemical Research
- Vol. 16 (3) , 215-226
- https://doi.org/10.1007/bf00966084
Abstract
Studies of the GABA-synthetic enzyme glutamate decarboxylase (glutamic acid decarboxylase; GAD; E.C.4.1.1.15) began in 1951 with the work of Roberts and his colleagues. Since then, many investigators have demonstrated the structural and functional heterogeneity of brain GAD. At least part of this heterogeneity derives from the existence of two GAD genes.Keywords
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