Treatment of Cirrhosis with Prednisone

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Abstract
To the Editor: From their controlled trial, the Copenhagen Study Group for Liver Diseases concluded that in patients with cirrhosis of the liver, prednisone therapy is only beneficial for nonalcoholic females without ascites.1 For nonalcoholic males no therapeutic effect was found, and for male and female patients with ascites, the death rate was in fact higher in those treated with prednisone.1 , 2 This statistical evidence would be more readily acceptable if the results conformed with general experience and took into account etiology. It is unusual that sex should determine response to therapy in liver disease. However, the distribution of different types . . .