Lignans and related phenols. Part 16. The biogenesis of podophyllotoxin
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- p. 2134-2136
- https://doi.org/10.1039/p19810002134
Abstract
The incorporation of DL-[β-14C]phenylalanine into podophyllotoxin (1) has been demonstrated. The subsequent stepwise degradation to 3′,4′-methylenedioxy-3,4,5-trimethoxybenzophenone bearing a 14C-carbonyl label establishes the in vivo synthesis of the carbon skeleton of this lignan.Keywords
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