Multisite clinical trials in alcoholism treatment research: organizational, methodological and management issues.
- 1 December 1994
- journal article
- review article
- Published by Alcohol Research Documentation, Inc. in Journal of Studies on Alcohol, Supplement
- Vol. 12 (s12) , 30-37
- https://doi.org/10.15288/jsas.1994.s12.30
Abstract
Multisite clinical trials have two major advantages over single-site studies: the large sample size of multisite studies allows for adequate statistical power and better representativeness of the population being studied. However, they are more complex to implement than single-site studies. This article reviews previous multisite clinical trials of alcohol abuse and alcoholism, reasons for selecting a multisite design, management of such studies, and some statistical issues.Keywords
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