Stoichiometry of catecholamine/proton exchange across the chromaffin-granule membrane
- 15 October 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 192 (1) , 273-278
- https://doi.org/10.1042/bj1920273
Abstract
Catecholamines are accumulated by bovine chromaffin-granule “ghosts” in the presence of MgATP at 25 degrees C. With low concentrations of catecholamine, ratios of internal to external amine concentration of up to 20 000 were obtained. These values fit well with a transport model in which amine accumulation is both electrogenic and dependent on a pH gradient across the membrane.This publication has 27 references indexed in Scilit:
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