Cycloheptadiene Ring Synthesis by Tandem Intermolecular Enyne Metathesis
- 26 August 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (19) , 3463-3466
- https://doi.org/10.1021/ol035246y
Abstract
The tandem intermolecular enyne metathesis between 1-alkynes and cyclopentene is reported, providing 2-substituted 1,3-cycloheptadienes. The success of the intermolecular reaction hinges on an appropriate balance between cycloalkene ring strain and reactivity of the alkyne.Keywords
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