The Action of Group Bm or CisAB Sera on Group O Red Cells in the Presence of UDP-D-Galactose
- 1 July 1975
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 29 (1) , 51-58
- https://doi.org/10.1111/j.1423-0410.1975.tb00476.x
Abstract
Group B and AB sera, acting on O red cells in the presence of UDP-galactose, each converted them into B active cells, which were agglutinated by anti-B human serum (1:512) at the titer of 128-fold, while group Bm and A-1 Bm sera, converted O red cells similarly incubated into B active cells, which were agglutinated by anti-B human serum (1:512) at the titer of 8- to 16-fold. This indicates that alpha-galactosyltransferase activity in Bm and A-1 Bm sera may be about 1/8-1/16 that in B and AB sera. Group CisAB sera, even after absorption of cold anti-B agglutinins with packed, washed group B red cells, did not convert O red cells in the presence of UDP-galactose in such a way that they might agglutinate against anti-B human serum.Keywords
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