Lung Cancer
Top Cited Papers
- 25 September 2008
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 359 (13) , 1367-1380
- https://doi.org/10.1056/nejmra0802714
Abstract
The Molecular Origins of Cancer series continues with this review of molecular and genetic mechanisms of lung cancer. The authors review genetic susceptibility to lung cancer and four genes of importance in the evolution of the disease: EGFR, KRAS, the PI3K–Akt–mTOR complex, and TITF1. They also discuss gene profiling and protein profiling, with emphasis on the clinical value of these methods.This publication has 136 references indexed in Scilit:
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