Mechanism of transfer of insecticides in Musca domestica

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Abstract
The onset of symptoms of toxicity in houseflies treated with poisons of the central nervous system (CNS) is shown to be delayed by measures which block metabolic activity such as depriving the insects of oxygen or decreasing the temperature. The indications from this work are that these measures also delay the penetration of the insecticide into the CNS. This suggests that the movement of the insecticide is mediated by a process which requires the expenditure of metabolic energy in a living tissue. The tissue most likely to be involved in insecticide transport is the epidermis.