Reversed-Phase Liquid Chromatographic Method for the Simultaneous Determination of Benomyl and Methyl lH-Benzimidazol-2-ylcarbamate in Wettable Powder Formulations
Open Access
- 1 November 1993
- journal article
- Published by Oxford University Press (OUP)
- Vol. 76 (6) , 1187-1192
- https://doi.org/10.1093/jaoac/76.6.1187
Abstract
A liquid chromatographic (LC) method is reported for the simultaneous determination of benomyl, methyl {1 -[(butylamino)carbonyl]-1 H-benzimidazol-2-yl}carbamate and carbendazim, methyl 1H-benzimidazol-2-ylcarbamate (MBC), in wettable powder (WP) formulations. In this method, benomyl is converted to 3-butyl-2,4-dioxo-s-triaz-ino[1,2-a]benzimidazole (STB) in 0.125M sodium hydroxide. After conversion (at room temperature in 20 min), STB is determined simultaneously with MBC (which remains intact with the sodium hydroxide treatment) at 286 nm after LC separation on a C18 column. The method was accurate and showed good reproducibility, with relative standard deviations of 0.7 and 2.2% for benomyl and MBC determinations, respectively.Keywords
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