Excretion of newly synthesized DNA by tonsil lymphocytes
- 1 January 1978
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 5 (8) , 3071-3080
- https://doi.org/10.1093/nar/5.8.3071
Abstract
The main part of newly synthesized DNA is preferentially released in vitro both by non-stimulated or phytohemagglutinin-stimulated tonsil lymphocytes. Freshly isolated cells excrete DNA faster than phytohemagglutinin-stimulated ones. The acid-precipitable 3H-thymidine lost can be accounted for in the culture medium as labeled, double stranded DNA isolated on hydroxyapatite column.Keywords
This publication has 19 references indexed in Scilit:
- Differences between human lymphocyte subpopulations with respect to the uptake and incorporation of [3H]uridine and ribonucleoside triphosphate poolsBiochemical Medicine, 1978
- Are endogenous C-type viruses involved in the immune system?Nature, 1977
- Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes.The Journal of Experimental Medicine, 1977
- Studies on DNA Release by Cultured Rat LymphoblastsInternational Archives of Allergy and Immunology, 1977
- Deoxyribonucleotide Pools in Mouse‐Fibroblast Cell Lines with Altered Ribonucleotide ReductaseEuropean Journal of Biochemistry, 1976
- DNA synthesis in tonsil lymphocytesBiochemical Medicine, 1976
- Characterization of DNA excreted from phytohemagglutinin-stimulated lymphocytes.The Journal of Experimental Medicine, 1976
- Determination of UTP and ATP pool sizes in human tonsillar lymphocytes by using Escherichia coli RNA polymeraseBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1975
- Isolation on discontinuous gradients of bovine albumin of a subpopulation of human lymphocytes exhibiting precursor characteristicsEuropean Journal of Immunology, 1975
- Generation of T Memory Cells in One-Way Mixed Lymphocyte Culture.Scandinavian Journal of Immunology, 1974