The genome of infectious bursal disease virus consists of two segments of double-stranded RNA
- 1 September 1979
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 31 (3) , 584-9
- https://doi.org/10.1128/jvi.31.3.584-589.1979
Abstract
The RNA of infectious bursal disease virus was reexamined in a detailed analysis. It could be established that its genome consists of two segments of double-stranded RNA. The RNA is RNase resistant and has a sedimentation coefficient of 14S and a buoyant density of 1.62 g/ml. The purine/pyrimidine ratio is nearly 1; the guanine plus cytosine content is 55.3%; the Tm is 95.5 degrees C. The molecular weights of the two double-stranded segments were determined to be 2.2 x 10(6) and 2.5 x 10(6).Keywords
This publication has 15 references indexed in Scilit:
- Mastomys natalensis Papilloma Virus (MnPV), the Causative Agent of Epithelial Proliferations: Characterization of the Virus ParticleJournal of General Virology, 1978
- The Structure of Infectious Pancreatic Necrosis Virus RNAJournal of General Virology, 1977
- Correlation between RNA fragments of fowl plague virus and their corresponding gene functionsVirology, 1976
- Structural and growth characteristics of two avian reovirusesArchiv für die gesamte Virusforschung, 1975
- Physico-chemical and Morphological Features of Infectious Pancreatic Necrosis VirusJournal of General Virology, 1973
- Analysis of bacteriophage T7 early RNAs and proteins on slab gelsJournal of Molecular Biology, 1973
- Detection of an Unstable RNA in Chick Fibroblasts after Reduction of the UTP Pool by GlucosamineEuropean Journal of Biochemistry, 1971
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970
- Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehydeJournal of Molecular Biology, 1968
- The Reaction of Ribonucleic Acid with Formaldehyde. I. Optical Absorbance Studies*Biochemistry, 1967