The kinetics of ?-granule formation: A morphometric study
- 1 May 1976
- journal article
- research article
- Published by Springer Nature in Diabetologia
- Vol. 12 (2) , 111-114
- https://doi.org/10.1007/bf00428974
Abstract
The rate of formation of β-granules in mouse islet cells has been studied by morphometry using experimental conditions in which insulin secretion is known to be blocked. The number of β-granules in a cell is increased by 120%, 45 minutes after a continued glucose stimulus of 16.7 mM. The implications of the results are discussed with respect to the construction of kinetic models for the secretion of insulin by exocytosis.This publication has 20 references indexed in Scilit:
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