EVALUATION OF GLYCOPYRROLATE AND ATROPINE AS ADJUNCTS TO REVERSAL OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS IN A “TRUE-TO-LIFE” SITUATION
Open Access
- 1 January 1980
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 52 (1) , 85-89
- https://doi.org/10.1093/bja/52.1.85
Abstract
Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a “true-to-life” situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease.Keywords
This publication has 1 reference indexed in Scilit:
- GLYCOPYRROLATE—NEOSTIGMINE MIXTURE FOR ANTAGONISM OF NEUROMUSCULAR BLOCK: COMPARISON WITH ATROPINE—NEOSTIGMINE MIXTUREBritish Journal of Anaesthesia, 1977