ACTOMYOSIN OF THE UTERUS

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Abstract
The contractile proteins, myo-sin (M) and actomysin (AM) were extracted from human striated muscle and from human and animal uterine muscle. The contraction of threads prepared from these materials was studied. Two differences were found between striated and uterine muscle. Uterine muscle contains less M + AM than striated muscle, and even the percentage of AM in the total sum of M+ AM is less. Threads prepd. from non-gravid uteri contract more slowly and to a smaller extent than threads from striated muscle. The total sum of AM + M and the percentage of AM increases during pregnancy in human and animal uteri. Both values reach their maxima during labor. Investigations carried out with rat and rabbit uteri show a significant increase of the AM percentage in the last period of gestation. The contraction of the threads increases with increasing values of the AM percentage, reaching the optimum during labor. In the rat the value for the sum of M + AM decreases after parturition.
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