Increased formation and decreased resorption of bone in mice with elevated vitamin D receptor in mature cells of the osteoblastic lineage
Open Access
- 1 October 2000
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 14 (13) , 1908-1916
- https://doi.org/10.1096/fj.99-1075com
Abstract
The microarchitecture of bone is regulated by complex interactions between the bone-forming and resorbing cells, and several compounds regulate both actions. For example, vitamin D, which is required...Keywords
Funding Information
- National Institutes of Health (1RO1-AR43421)
This publication has 38 references indexed in Scilit:
- The Therapy of Osteoporosis and the Importance of Cortical BoneCalcified Tissue International, 1997
- The effects of long-term hormone replacement therapy on bone remodeling in postmenopausal womenBone, 1996
- Current bone mineral density data on bisphosphonates in postmenopausal osteoporosisBone, 1996
- Vitamin D Supplementation and Fracture Incidence in Elderly PersonsAnnals of Internal Medicine, 1996
- Relations between histologic indices of bone formation: Implications for the pathogenesis of spinal osteoporosisJournal of Bone and Mineral Research, 1995
- Characterization of the 1,25-(OH)2D3-induced inhibition of bone nodule formation in long-term cultures of fetal rat calvaria cellsEndocrinology, 1993
- Treatment of Postmenopausal Osteoporosis with Calcitriol or CalciumNew England Journal of Medicine, 1992
- Pleiotropic Effects of Vitamin D on Osteoblast Gene Expression Are Related to the Proliferative and Differentiated State of the Bone Cell Phenotype: Dependency upon Basal Levels of Gene Expression, Duration of Exposure, and Bone Matrix Competency in Normal Rat Osteoblast Cultures*Endocrinology, 1991
- Treatment of Postmenopausal Osteoporosis with High Doses of Synthetic CalcitriolAnnals of Internal Medicine, 1990
- Calcitriol Treatment Is Not Effective in Postmenopausal OsteoporosisAnnals of Internal Medicine, 1989