Active transendothelial transport of albumin. Interstitium to lumen.
- 1 December 1985
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 57 (6) , 903-908
- https://doi.org/10.1161/01.res.57.6.903
Abstract
Cultured porcine pulmonary artery endothelial monolayers actively transport albumin from interstitium to lumen. The active process favors interstitial to luminal transport by a factor of 10 even in the face of a 2:1 luminal:interstitial albumin gradient. The active process is abolished by treatment with 1 mM sodium cyanide. Dextran is not actively transported. This process could be important in determining transvascular fluid balance and transfer of macromolecules across the endothelium.This publication has 2 references indexed in Scilit:
- Receptor-Mediated Transport of Insulin Across Endothelial CellsScience, 1985
- Capillary transport of macromolecules: pores and other endothelial pathwaysJournal of Applied Physiology, 1985