Actinorhodin is a Chromosomally-determined Antibiotic in Streptomyces coelicolor A3(2)
- 1 October 1976
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 96 (2) , 289-297
- https://doi.org/10.1099/00221287-96-2-289
Abstract
S. coelicolor A3(2) synthesizes a 2nd antibiotic in addition to the plasmid-determined methylenomycin A. It was identified, primarily by mass spectroscopy of its diethyl ester, as actinorhodin, which was described previously in other strains. It inhibited most gram-positive bacteria tested, but only at a comparatively high concentration. Five independent mutations leading to lack of actinorhodin synthesis were located between cysD and strA on the chromosome.This publication has 1 reference indexed in Scilit:
- LINKAGE AND THE MECHANISM OF RECOMBINATION IN STREPTOMYCES COELICOLOR*Annals of the New York Academy of Sciences, 1959