Lympho-epithelial thymomas A retrospective study of 88 resections

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Abstract
Of 113 lympho-epithelial thymomas retrospectively studied, 56 wereepithelial, 20 lymphocytic, 30 mixed and 7 were undefined forms. There were88 resections (20 stage I, 47 stage II, 13 stage III and 8 stage IV). Therewere 69 primary resections (followed by radiotherapy in 54 cases) of which57 were complete and 12 were incomplete. There were 19 secondary resectionsafter radiotherapy: 10 were complete and 9 were incomplete and 25 patientswere not operated upon and were treated by radio- and chemotherapy. Afterprimary resection, the actuarial 5-year survival is 64.07% and the 10-yearsurvival is 50.86%. After a secondary resection, the 5 year-survival is43.74%. After non-surgical treatment, it is 18.67%. After surgery, theprognostic importance of staging is confirmed as more important than thecellular structure. Myasthenic patients are subject to late accidents.Postoperative radiotherapy seems to be justified, but its effect is notstatistically significant when resection is complete. Post-radiotherapysurgery is beneficial only in cases of complete resection. The metastaticevolution of thymomas has been underrated and seems to depend upon thelocal control of the tumour. The use of chemotherapy remains to bedefined.

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