Efficacy of the Topical Anesthetic Cream, EMLA, in Alleviating Both Needle Insertion and Injection Pain
- 1 December 1995
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Annals of Plastic Surgery
- Vol. 35 (6) , 576-579
- https://doi.org/10.1097/00000637-199512000-00003
Abstract
To assess the efficacy of the topical anesthetic cream, EMLA, in alleviating the pain produced by infiltration of local anesthetic prior to surgical skin biopsies, a randomized, double-blind, placebo-controlled study was performed on 54 patients undergoing 162 excisional biopsies. Both pain induced by needle insertion and pain induced by local injection were significantly diminished after topical application of EMLA cream. However, part of the effect was placebo, because the placebo ointment (Vaseline) also produced significant pain alleviation.Keywords
This publication has 0 references indexed in Scilit: