Immunohistochemical Characterization of Thyrotropin-Releasing Hormone-Containing Neurons in Rat Septum
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 39 (5) , 448-452
- https://doi.org/10.1159/000124019
Abstract
A sensitive and specific immunohistochemical technique has been used to reveal the distribution of thyrotropin-releasing hormone (TRH) in extrahypothalamic regions. Numerous cell bodies of the lateral septum were surrounded by profiles of dense, spotted TRH-containing axon terminals, suggesting the presence of synaptic contacts. The immunoreactive TRH was found to decrease markedly after electrolytic lesion of the medial preoptic area. The same lesions also lowered the septal content of TRH to 65%, as estimated by radioimmunoassay.This publication has 3 references indexed in Scilit:
- Distribution of Immunoreactive Human Growth Hormone-Like Material and Thyrotropin-Releasing Hormone in the Rat Central Nervous System: Evidence for Their Coexistence in the Same Neurons*Endocrinology, 1983
- Immunohistochemical Localization of Thyrotropin-Releasing Hormone in the Rat Hypothalamus and Pituitary*Endocrinology, 1982
- Effects of thyrotropin releasing hormone injections into different loci of rat brain on core temperatureNeuroscience Letters, 1981