Pd(II)–Cu(II)-CATALYZED SYNTHESIS OF MONO- AND DIALKENYL-SUBSTITUTED FIVE-MEMBERED AROMATIC HETEROCYCLES

5 October 1979

journal article
Published by Oxford University Press (OUP) in Chemistry Letters

Vol. 8 (10) , 1229-1230
https://doi.org/10.1246/cl.1979.1229

Abstract

The Pd-catalyzed one-step alkenylation method of five-membered aromatic heterocycles such as furan or thiophene with olefins has been found. The reaction proceeds regioselectively occurring at the 2-position of the heterocycles and the products have trans-stereochemistry when the substituents on the olefin is bulky.

Keywords

AROMATIC HETEROCYCLES
DIALKENYL SUBSTITUTED
MEMBERED AROMATIC
CATALYZED SYNTHESIS

This publication has 1 reference indexed in Scilit:

Aromatic substitution of olefins. XXV. Reactivity of benzene, naphthalene, ferrocene, and furan toward styrene, and the substituent effect on the reaction of monosubstituted benzenes with styrene
The Journal of Organic Chemistry, 1976