Reaction of 8,2′-O-cycloadenosine with hydrazine and amines. Convenient preparations of 9-β-D-arabinofuranosyladenine and its derivatives
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 12,p. 414-415
- https://doi.org/10.1039/c39770000414
Abstract
Reaction between 8,2′-O-cycloadenosine (2) and hydrazine gives a high yield of (1b) which on oxidation with yellow mercuric oxide is converted into ara-A (1a) in quantitative yield; reaction between (2) and the appropriate amines gives the 8-amino-ara-A derivatives (1c–g) in good to high yields.This publication has 2 references indexed in Scilit:
- Chemotherapy of Virus DiseasesAngewandte Chemie International Edition in English, 1976
- Interconversion of 8,2′-O-cycloadenosine and 2′,3′-anhydro-8-oxyadenosineJournal of the Chemical Society, Chemical Communications, 1976