THE EXPERIMENTAL PRODUCTION OF OVULATION, LUTEINIZATION AND CYSTS OF THE CORPUS LUTEUM IN ADRENALECTOMIZED ANESTROUS CATS

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Abstract
The ovarian follicles of 13 normal anestrous cats and 11 adrenalectomized anestrous cats were matured and ovu-lated by the admin. of FSH and LH according to the method of Foster and Hisaw. The process of ovulation and of subsequent luteinization was delayed significantly in the animals which had been adrenalectomized prior to injection with FSH and LH. This was detd. by histo-logical exam. of the recovered ova, by observation of the spontaneous motility of the uterus and of its reaction to adrenalin, and by measurements of the height of the uterine glandular epithelium and of the diameter of the uterine glands. Corpus luteum cysts were found in the ovaries of both normal and adrenalectomized animals, but were much more striking in size in the latter group. These huge lutein cysts, measuring 5 to 7 mm. in diam., were also present in the ovaries of cats adequately supported by cortin.