Chlorpromazine in Women with Chronic Schizophrenia: The Effect on Cholesterol Levels and Cholesterol-Behavior Relationships
- 1 November 1967
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Psychosomatic Medicine
- Vol. 29 (6) , 634-642
- https://doi.org/10.1097/00006842-196711000-00008
Abstract
In 2 carefully controlled studies with the same women with chronic schizophrenia, chlorpromazine was shown to raise serum cholesterol levels consistently and significantly. It was also a consistent finding that prior to chlorpromazine therapy cholesterol levels appeared to be related inversely to measures of withdrawal, seclusiveness, and gross psychopathology. After chlorpromazine therapy the cholesterol-behavior relationships were no longer apparent.Keywords
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