DEFECTIVE LOW-DENSITY CELLS OF DENDRITIC MORPHOLOGY FROM THE BLOOD OF PATIENTS WITH COMMON VARIABLE HYPOGAMMAGLOBULINEMIA - LOW IMMUNOGLOBULIN PRODUCTION ON STIMULATION OF NORMAL B-CELLS
- 1 January 1985
- journal article
- research article
- Vol. 61 (1) , 189-194
Abstract
Low-density cells (LDC) of dendritic morphology from the blood of patients with common variable (late-onset) hypogammaglobulinemia (CVH) did not include allogeneic Ig production by normal B cells unlike LDC from normal blood. When LDC from patients were treated with pokeweed mitogen (PWM), a lower allogeneic secretion of IgM and IgG was induced in normal B cells than that induced by allogeneic normal LDC treated with PWM. B cells from hypogammaglobulinemic patients were non-responsive to both normal and patient LDC treated with PWM under all conditions tested.This publication has 9 references indexed in Scilit:
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