Novel biotransformation of a 2-pyrone to a substituted benzoic acid.
Open Access
- 1 January 1985
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 33 (11) , 5141-5143
- https://doi.org/10.1248/cpb.33.5141
Abstract
It was found that Macrophoma commelinae (IFO 9570) had an ability to transform 5-acetyl-4-methoxy-6-methyl-2-pyrone (1) to 4-acetyl-3-methoxy-5-methylbenzoic acid (2). This biotransformation was investigated using 13C- and 14C-labeled compounds. It is likely that 2 is formed by condensation of the added 2-pyrone and a catabolic pyruvateKeywords
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