PKBα/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
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- 1 April 2008
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 30 (2) , 203-213
- https://doi.org/10.1016/j.molcel.2008.02.024
Abstract
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This publication has 41 references indexed in Scilit:
- Loss of nuclear p21Cip1/WAF1 during neoplastic progression to metastasis in γ-irradiated p21 hemizygous miceExperimental and Molecular Pathology, 2007
- Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaksThe Journal of cell biology, 2007
- Intramolecular and Intermolecular Interactions of Protein Kinase B Define Its Activation In VivoPLoS Biology, 2007
- Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaksThe Journal of cell biology, 2006
- Glycogen Synthase Kinase 3-Dependent Phosphorylation of Mdm2 Regulates p53 AbundanceMolecular and Cellular Biology, 2005
- Chromatin in Need of a Fix: Phosphorylation of H2AX Connects Chromatin to DNA RepairMolecular Cell, 2005
- Activation of the DNA damage checkpoint and genomic instability in human precancerous lesionsNature, 2005
- DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisNature, 2005
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR ComplexScience, 2005
- Mechanism and regulation of human non-homologous DNA end-joiningNature Reviews Molecular Cell Biology, 2003