Reissert compound chemistry. Part II. Synthesis of 1-benzylisoquinolines via the Reissert carbanion generated with sodium hydride
- 1 January 1969
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- No. 4,p. 666-668
- https://doi.org/10.1039/j39690000666
Abstract
An improved procedure for the preparation of 1-benzylisoquinolines in high overall yields via Reissert compound intermediates has been developed. It involves generation of the C-1 carbanion of the Reissert compound with sodium hydride in dimethylformamide.Keywords
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