Isotope Effect Studies on the Cytochrome P450 Enzymes
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in Drug Metabolism Reviews
- Vol. 27 (1-2) , 45-59
- https://doi.org/10.3109/03602539509029814
Abstract
(1995). Isotope Effect Studies on the Cytochrome P450 Enzymes. Drug Metabolism Reviews: Vol. 27, No. 1-2, pp. 45-59. doi: 10.3109/03602539509029814Keywords
This publication has 22 references indexed in Scilit:
- Use of aromatase metabolite ratios to characterize electron transfer from NADPH-cytochrome P450 reductaseBiochemistry, 1993
- Intrinsic isotope effects suggest that the reaction coordinate symmetry for the cytochrome P-450-catalyzed hydroxylation of octane is isozyme independentJournal of Medicinal Chemistry, 1990
- Theory for the observed isotope effects from enzymic systems that form multiple products via branched reaction pathways: cytochrome P-450Biochemistry, 1989
- The separation of the intramolecular isotope effect for the cytochrome P-450 catalyzed hydroxylation of n-octane into its primary and secondary componentsJournal of the American Chemical Society, 1987
- Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: a new method for the estimation of intrinsic isotope effectsJournal of the American Chemical Society, 1986
- Model systems for cytochrome P450 dependent mono-oxygenases. Part 2. Kinetic isotope effects for the oxidative demethylation of anisole and [Me-2H3]anisole by cytochrome P450 dependent mono-oxygenases and model systemsJournal of the Chemical Society, Perkin Transactions 2, 1983
- Use of Isotope Effects to Elucidate Enzyme MechanismCritical Reviews in Biochemistry, 1982
- The Expression of Isotope Effects on Enzyme-Catalyzed ReactionsAnnual Review of Biochemistry, 1981
- Aliphatic hydroxylation by highly purified liver microsomal cytochrome P-450. Evidence for a carbon radical intermediateBiochemical and Biophysical Research Communications, 1978
- Intramolecular determination of primary kinetic isotope effects in hydroxylations catalyzed by cytochrome P-450Biochemical and Biophysical Research Communications, 1977