Improved Synthesis of Tricyclo (5.2.1.04,10) Decane-2,5,8-Trione by a Pauson-Khand Intramolecular Bis-Annulation
- 1 April 1988
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 18 (4) , 381-390
- https://doi.org/10.1080/00397918808064001
Abstract
The title compound 1 has been synthesized from diol 3a, either directly or after protection of the two hydroxy groups as benzyl ethers, by an intramolecular Pauson-Khand bis-annulation, followed by catalytic hydrogenation and oxidation in overall yields ranging from 15% (free diol) to 35% (dibenzyl ethers).Keywords
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