Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic.
- 1 January 1993
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 46 (7) , 1076-1081
- https://doi.org/10.7164/antibiotics.46.1076
Abstract
A new antitumor antibiotic vicenistatin was isolated from the culture broth of Streptomyces sp. HC34. The structure of vicenistatin was elucidated by NMR spectral analysis. Vicenistatin exhibited antitumor activity against human colon carcinoma Co-3 in the xenograft model.Keywords
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