New Fluorescent Tools for Watching Nanometer-Scale Conformational Changes of Single Molecules
- 1 June 2007
- journal article
- review article
- Published by Annual Reviews in Annual Review of Biophysics
- Vol. 36 (1) , 349-369
- https://doi.org/10.1146/annurev.biophys.36.040306.132700
Abstract
Single-molecule biophysics has been serving biology for more than two decades. Fluorescence microscopy is one of the most commonly used tools to identify molecules of interest and to visualize biological events. Here we describe some of the most commonly used fluorescence imaging tools to measure nanoscale movements and the rotational dynamics of biomolecules.Keywords
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