Dna repair synthesis in subpopulations of human lymphocytes
Open Access
- 1 April 1982
- journal article
- research article
- Published by The Company of Biologists in Journal of Cell Science
- Vol. 54 (1) , 69-78
- https://doi.org/10.1242/jcs.54.1.69
Abstract
Human peripheral blood lymphocytes enriched in T or B cells were exposed to ultraviolet irradiation, nitrogen mustard or methylmethane sulphonate and investigated regarding their capacity for DNA repair synthesis. The DNA repair synthesis, measured as [3H]thymidine incorporated, was determined by autoradiography as unscheduled DNA synthesis (LIDS). No systematic difference could be found in the capacity for UDS between the T- and B-cell-enriched fractions. A larger individual variation in UDS was found in the B-cell-compared to the T-cell-enriched lymphocytes.This publication has 15 references indexed in Scilit:
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