Zur Umwandlung von 17β-Hydroxy-östra-p-chinol-(10β) in 3-Amino-Δ1.3.5.(10)-östratrienol-(17β)

Abstract
17[beta]-Hydroxy-estra-p-quinol-(10[beta]) reacts with pyridoxamine (added as the dihydrochloride) in ethanol-phosphate buffer, pH 7.3, to give a Schiff''s base. Hydrolysis of this base gives 3-amino- [DELTA] 1,3,5(10). estratrienol-(17[beta]). A Schiff''s base can also be prepared from the latter amine and pyridoxal (as the ethyl half acetal hydrochloride). The 2 Schiff''s bases have different UV-spectra.

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