AGE AND SEX DEPENDENCE OF SPONTANEOUS FREQUENCY OF CHROMOSOME-ABERRATIONS IN HUMAN PERIPHERAL-BLOOD LYMPHOCYTES .1. AGE DYNAMICS OF SPONTANEOUS FREQUENCY OF CHROMOSOME-ABERRATIONS AND ABERRANT CELLS IN PERIPHERAL-BLOOD LYMPHOCYTES

  • 1 January 1980
    • journal article
    • research article
    • Vol. 16  (7) , 1285-1293
Abstract
Spontaneous frequency of chromosome aberrations in 680 individuals of both sexes (from newborns to centenarians) was studied. The age dependence of the frequency of chromosome aberrations was revealed. The distribution of individuals according to the frequency of their chromosome aberrations corresponds to Poisson''s law. The analysis of the age dynamics of the frequency of chromosome aberrations made it possible to define 3 age periods. The 1st period involves newborns with a high level of chromosome aberrations; the 2nd period involves individuals at the age of 1-20 yr with the lowest level of aberrations and the 3rd one involves individuals over 30 yr old with continuous increase in the spontaneous frequency of chromosome aberrations with the age.

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