Measurement of the Insulin Delivery Rate in Man
- 1 August 1971
- journal article
- clinical trial
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 33 (2) , 279-286
- https://doi.org/10.1210/jcem-33-2-279
Abstract
A method for the quantitative assessment of rapid changes in the delivery rate of hormones into the systemic circulation is reported. Plasma hormone levels are examined in relation to the “non-steady-state” disappearance rate measured following an intravenous infusion of the hormone. The insulin delivery rate in response to iv glucose has been measured; a biphasic insulin response has been confirmed; and the amount of insulin entering the systemic circulation in each phase can be examined.Keywords
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