Lactate Dehydrogenase Variant from Human Blood: Evidence for Molecular Subunits
- 16 August 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 141 (3581) , 642-643
- https://doi.org/10.1126/science.141.3581.642
Abstract
A variant of human lactate dehydrogenase is described. The occurrence of lactate dehydrogenase-1, -2, -3, and -4 as five, four, three, and two components, respectively, is interpreted as supporting the hypothesis that LDH isozymes are tetramers formed from various combinations of two types of subunits.Keywords
This publication has 15 references indexed in Scilit:
- Lactate Dehydrogenase Isozymes: Dissociation and Recombination of SubunitsScience, 1963
- Lactic Dehydrogenases: Subfractionation of IsozymesScience, 1963
- Lactate Dehydrogenases in Human TestesScience, 1963
- ERYTHROCYTE METABOLISM. VI. SEPARATION OF ERYTHROCYTE ENZYMES FROM HEMOGLOBIN*Journal of Clinical Investigation, 1962
- Variations in the Lactic Dehydrogenase of Vertebrate ErythrocytesThe Journal of general physiology, 1962
- Dissociation of lactate dehydrogenase into subunits with guanidine hydrochlorideBiochemical and Biophysical Research Communications, 1961
- EVOLUTION AND DIFFERENTIATION OF DEHYDROGENASES*Annals of the New York Academy of Sciences, 1961
- ISOZYMES OF LACTIC DEHYDROGENASE IN HUMAN TISSUES*Journal of Clinical Investigation, 1961
- Starch Gel Electrophoresis of Lactic Dehydrogenase from Rat Kidney.Experimental Biology and Medicine, 1960
- Starch Gel Electrophoresis in a Discontinuous System of BuffersNature, 1957