Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids
- 1 January 1998
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 18,p. 2039-2040
- https://doi.org/10.1039/a805364b
Abstract
An acid catalysed ring rearrangement of a triflate derivative of D-mannono-?-lactone 6 is the key step in the synthesis of the C-glycosyl sugar amino acid derivatives 3 and 4, examples of carbohydrate amino acid building blocks with specific conformational preferences suitable for incorporation into combinatorial amide libraries; homo-oligomerisation via solution phase coupling procedures affords furanose carbopeptoids 1 which adopt novel solution state secondary structures.Keywords
This publication has 0 references indexed in Scilit: