The rate of adhesion of melanoma cells onto nonionic polymer surfaces
- 1 September 1978
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research
- Vol. 12 (5) , 701-706
- https://doi.org/10.1002/jbm.820120510
Abstract
The rates of adhesion of melanoma cells (carcinogenic) onto nonionic polymer surfaces were studied by using radioactively labeled cells and measuring the fraction of cells which adhered to the surface in a given time. Glow discharge (plasma) polymerization of 1,1,3,3‐tetramethyldisiloxane and of nitrogen‐acetylene‐water (mole ratio 0.4:1.0:0.2) was used to modify the surface energy of the substrate. The cell adhesion rate was found to be given by Y = 1 − exp [−k0(γs − γ0)t], where Y is the fraction of cells adhered, − k0 is a characteristic rate constant, γs is the total surface energy of the substrate, γ0 is the threshold surface energy of cell adhesion, and t is time.This publication has 3 references indexed in Scilit:
- Some aspects of plasma copolymerization of acetylene with N2 and/or waterJournal of Polymer Science: Polymer Chemistry Edition, 1977
- Plasma polymerization of some organic compounds and properties of the polymersJournal of Polymer Science: Polymer Chemistry Edition, 1976
- Ultrathin coating by plasma polymerization applied to corneal contact lensJournal of Biomedical Materials Research, 1975