Lymphocytic Choriomeningitis Virus — An Old Enemy up to New Tricks
- 25 May 2006
- journal article
- editorial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 354 (21) , 2208-2211
- https://doi.org/10.1056/nejmp068021
Abstract
Lymphocytic choriomeningitis virus (LCMV) was among the first human pathogenic viruses to be isolated. In the mid-1930s, Armstrong and Lillie obtained a filterable agent thought to be from the brain of a man who died during an epidemic of St. Louis encephalitis, Traub discovered a chronic infection in a mouse colony, and Rivers and Scott isolated a virus from the cerebrospinal fluid of patients with aseptic meningitis (see image).1 All three of these viruses were shown to have the same properties and serologic features, and LCMV became the type species characterizing the virus family Arenaviridae, established in 1970. In nature, . . .Keywords
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