Heterogeneous three-dimensional anatomical and electrophysiological model of human atria
Open Access
- 12 April 2006
- journal article
- Published by The Royal Society in Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
- Vol. 364 (1843) , 1465-1481
- https://doi.org/10.1098/rsta.2006.1781
Abstract
Investigating the mechanisms underlying the genesis and conduction of electrical excitation in the atria at physiological and pathological states is of great importance. To provide knowledge concerning the mechanisms of excitation, we constructed a biophysical detailed and anatomically accurate computer model of human atria that incorporates both structural and electrophysiological heterogeneities.Keywords
This publication has 24 references indexed in Scilit:
- Enabling computer models of the heart for high-performance computers and the gridPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2006
- Post-genomic science: cross-disciplinary and large-scale collaborative research and its organizational and technological challenges for the scientific research processPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2006
- Role of up-regulation of in action potential shortening associated with atrial fibrillation in humansCardiovascular Research, 2005
- Human Study of Biatrial Electrical CouplingCirculation, 2004
- Structure and function of the sinus node, AV node and his bundle of the human heart: Part II–functionProgress in Cardiovascular Diseases, 2003
- Structure and function of the sinus node, AV node and his bundle of the human heart: Part I—StructureProgress in Cardiovascular Diseases, 2002
- Control of the pacemaker activity of the sinoatrial node by intracellular Ca 2+ . Experiments and modellingPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2001
- A computer model of human atria with reasonable computation load and realistic anatomical propertiesIEEE Transactions on Biomedical Engineering, 2001
- Electrophysiologic Properties of the Adult Human Sinus NodeJournal of Cardiovascular Electrophysiology, 1997
- Thin collagenous septa in cardiac muscleThe Anatomical Record, 1987