Specificity of esterases and structures of prodrug esters. III. Activity of rat tissue homogenates, rat plasma and porcine liver esterase for the hydrolysis of 3',5'-bis-dicarboxylic acid hemiesters of 5-fluoro-2'-deoxyuridine.
- 1 January 1985
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 33 (7) , 2956-2961
- https://doi.org/10.1248/cpb.33.2956
Abstract
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This publication has 7 references indexed in Scilit:
- Specificity of esterases and structure of prodrug esters. II. Hydrolytic regeneration behavior of 5-fluoro-2'-deoxyuridine (FUdR) from 3',5'-diesters of FUdR with rat tissue homogenates and plasma in relation to their antitumor activity.CHEMICAL & PHARMACEUTICAL BULLETIN, 1985
- Methotrexate analogs. 21. Divergent influence of alkyl chain length on the dihydrofolate reductase affinity and cytotoxicity of methotrexate monoestersJournal of Medicinal Chemistry, 1984
- Synthesis and evaluation of a series of 2'-O-acyl derivatives of 9-.beta.-D-arabinofuranosyladenine as antiherpes agentsJournal of Medicinal Chemistry, 1984
- O-acylsalicylamides as possible prodrugs for salicylamide I. Kinetics and mechanisms of their degradation and reaction with enzymes and sodium bisulfiteInternational Journal of Pharmaceutics, 1983
- Development of lipophilic prodrugs of mitomycin C. III. Physicochemical and biological properties of newly synthesized alkoxycarbonyl derivatives.CHEMICAL & PHARMACEUTICAL BULLETIN, 1983
- Age-related changes in esterase activity in rabbit eyesInternational Journal of Pharmaceutics, 1983
- COMPARISON OF CYTOTOXIC EFFECT AND CELLULAR UPTAKE OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE AND ITS N4-ACYL DERIVATIVES, USING CULTURED KB CELLS1979